Bladder malacoplakia and bilateral hydronephrosis: a case report




Israel Arellano-Romero, Departamento Institucional Adscrito, Servicio de Urología, Hospital Regional ISSSTE, Benemérita Universidad Autónoma de Puebla, Puebla, Pue., México
Gerardo Moreno-Pérez, Departamento Institucional Adscrito, Servicio de Urología, Hospital Regional ISSSTE, Benemérita Universidad Autónoma de Puebla, Puebla, Pue., México
Juan P. Landaverde-Sandoval, Departamento Institucional Adscrito, Servicio de Urología, Hospital Regional ISSSTE, Benemérita Universidad Autónoma de Puebla, Puebla, Pue., México
Eduardo Guzmán-Emiliano, Departamento Institucional Adscrito, Servicio de Urología, Hospital Regional ISSSTE, Benemérita Universidad Autónoma de Puebla, Puebla, Pue., México
Roberto E. Chapa-Abrego, Departamento Institucional Adscrito, Servicio de Urología, Hospital Regional ISSSTE, Benemérita Universidad Autónoma de Puebla, Puebla, Pue., México


Malacoplakia is a chronic granulomatous disease associated with immunosuppression and infection that mainly affects the bladder. It is characterized by the presence of nodules, plaques or ulcers in the bladder, lower urinary tract symptoms and hematuria. It can mimic the clinical picture of bladder cancer. The case of a 66-year-old female patient with hematuria and lower urinary tract symptoms is presented. Initially, high-grade urothelial carcinoma was diagnosed, but after histopathological review, the diagnosis of malacoplakia was confirmed. Medical treatment was started, and the condition is currently in remission. Malacoplakia is an extremely rare disease that should be considered in patients with recurrent urinary tract infections and tumor findings on cystoscopy, since it can be confused with bladder cancer. Early diagnosis and treatment are important to avoid unnecessary surgical interventions and associated complications.



Keywords: Malakoplakia. Bladder cancer. Bilateral hydronephrosis. Hematuria. Case report.